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Product Name:glucosamine and Chondroitin sulfate

glucosamine and Chondroitin sulfate source: Chondroitin sufphate is an acid mucopolysaccharide extracted from fish or bovine cartilage.

glucosamine and Chondroitin sulfate introduction:Chondroitin sulfate sodium is the sodium salt of the sulfated linear glycosaminoglycan obtained from bovine, porcine, or avian cartilages of healthy and domestic animals used for food by humans.

Appearance: Creamy white powder

glucosamine and Chondroitin sulfate specifications: 90% 95% 98% chondroitin Sulfate chondroitin >95%, Calcium>6.5%; Sodium<0.5%

Test By:               HPLC/CPC

Molecular formula:     (C12H21NO14S) n

Molecular weight:       30000-50000

Structural formula:

glucosamine and Chondroitin sulfate Main benefits:

Chondroitin's functions depend largely on the properties of the overall proteoglycan of which it is a part. These functions can be broadly divided into structural and regulatory roles. However, this division is not absolute, and some proteoglycans have both structural and regulatory roles (see versican).

Chondroitin sulfate is a major component of extracellular matrix, and is important in maintaining the structural integrity of the tissue. This function is typical of the large aggregating proteoglycans: aggrecan, versican, brevican, and neurocan, collectively termed the lecticans.

As part of aggrecan, Chondroitin sulfate is a major component of cartilage. The tightly packed and highly charged sulfate groups of Chondroitin sulfate generate electrostatic repulsion that provides much of the resistance of cartilage to compression. Loss of chondroitin sulfate from the cartilage is a major cause of osteoarthritis.

glucosamine and Chondroitin sulfate specification


          ITEMS

STANDARD

RESULTS

Clarity and Color of Solution

0.35 Max at 420nm

PASS                               

Appearance

White to Off-white Free Flowing Powder

PASS

Heavy Metals (Pb)

20PPM Max

PASS

Chloride

0.5% Max

PASS

Sulfate

0.24% Max

PASS

Specific Rotation

-20.0° -30.0°

-23.0°

Chondroitin Sulfate Assay (CPC)

90% Min ( O.D.B)

91.6%

Bluk density

0.6Min

0.63

Particle size

100%through 80mesh

PASS

Chondroitin Sulfate Assay (HPLC)

90% Min ( O.D.B)

90.2%

Content of Protein

6.0% Max (Dried Basis)

3.3%

Residue On Ignition

20%-30%

22.0%

Loss On Drying

10% Max

8.5%

PH

5.5-7.5

6.4

glucosamine and Chondroitin sulfate Microbiological Tests

Clostridium

Negative

NEGATIVE

E.Coli

Negative

NEGATIVE

Total Plate Count

1,000cfu/g Max

PASS

Yeast & Mold

100cfu/g Max

PASS

Salmonella

Negative

NEGATIVE

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