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Product Name:glucosamine and Chondroitin sulfate
glucosamine and Chondroitin sulfate source: Chondroitin sufphate is an acid mucopolysaccharide extracted from fish or bovine cartilage.
glucosamine and Chondroitin sulfate introduction:Chondroitin sulfate sodium is the sodium salt of the sulfated linear glycosaminoglycan obtained from bovine, porcine, or avian cartilages of healthy and domestic animals used for food by humans.
Appearance: Creamy white powder
glucosamine and Chondroitin sulfate specifications: 90% 95% 98% chondroitin Sulfate chondroitin >95%, Calcium>6.5%; Sodium<0.5%
Test By: HPLC/CPC
Molecular formula: (C12H21NO14S) n
Molecular weight: 30000-50000
Structural formula:
glucosamine and Chondroitin sulfate Main benefits:
Chondroitin's functions depend largely on the properties of the overall proteoglycan of which it is a part. These functions can be broadly divided into structural and regulatory roles. However, this division is not absolute, and some proteoglycans have both structural and regulatory roles (see versican).
Chondroitin sulfate is a major component of extracellular matrix, and is important in maintaining the structural integrity of the tissue. This function is typical of the large aggregating proteoglycans: aggrecan, versican, brevican, and neurocan, collectively termed the lecticans.
As part of aggrecan, Chondroitin sulfate is a major component of cartilage. The tightly packed and highly charged sulfate groups of Chondroitin sulfate generate electrostatic repulsion that provides much of the resistance of cartilage to compression. Loss of chondroitin sulfate from the cartilage is a major cause of osteoarthritis.
glucosamine and Chondroitin sulfate specification
ITEMS |
STANDARD |
RESULTS |
Clarity and Color of Solution |
0.35 Max at 420nm |
PASS |
Appearance |
White to Off-white Free Flowing Powder |
PASS |
Heavy Metals (Pb) |
20PPM Max |
PASS |
Chloride |
0.5% Max |
PASS |
Sulfate |
0.24% Max |
PASS |
Specific Rotation |
-20.0° — -30.0° |
-23.0° |
Chondroitin Sulfate Assay (CPC) |
90% Min ( O.D.B) |
91.6% |
Bluk density |
0.6Min |
0.63 |
Particle size |
100%through 80mesh |
PASS |
Chondroitin Sulfate Assay (HPLC) |
90% Min ( O.D.B) |
90.2% |
Content of Protein |
6.0% Max (Dried Basis) |
3.3% |
Residue On Ignition |
20%-30% |
22.0% |
Loss On Drying |
10% Max |
8.5% |
PH |
5.5-7.5 |
6.4 |
glucosamine and Chondroitin sulfate Microbiological Tests |
||
Clostridium |
Negative |
NEGATIVE |
E.Coli |
Negative |
NEGATIVE |
Total Plate Count |
1,000cfu/g Max |
PASS |
Yeast & Mold |
100cfu/g Max |
PASS |
Salmonella |
Negative |
NEGATIVE |