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Product Name: Levodepa
Levodepa source: L-DOPA (L-3,4-dihydroxyphenylalanine; INN Levodopa; trade names Sinemet, Parcopa, Atamet, Stalevo, Madopar, Prolopa, etc.) is a naturally occurring dietary supplement and psychoactive drug found in certain kinds of food and herbs (e.g., Mucuna pruriens, or velvet bean), and is synthesized from the amino acid L-tyrosine in the mammalian body and brain. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) collectively known as catecholamines. Aside from its natural and essential biological role, L-DOPA is also used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia. When used in a pharmaceutical context, the INN designation 'Levodopa' is normally used.
Levodepa introduction: Mucuna Pruriens also call dog claw bean, the seed of Stizolobium cochinchin ensis (Lour). Tang et Wang. Seed capsule is black or off-white. This species plant is abundantly grows in tropic and sub-tropic area inChina, Guangxi also have widely growth. Its main effective ingredient is Levodopa. Levodopa is mainlyuse in treatment of parkinsonism, liver stupor, fracture, neuralgia etc.
Appearance: White or White Crystal powder
Active ingredient: Levodopa L-Dopa
Levodepa specifications: Mucuna Pruriens Extract (L-dopa) Upto 50% L-dopa by HPLC
Test By: HPLC
Molecular formula: C9H11NO4
Molecular weight: 197.19
Structural formula:
Levodepa Main benefits:
1. In clinical use, Mucuna Pruriens Extract is
administered in the management of Parkinson's disease and dopa-responsive
dystonia.
2. For essential tremor and paralysis paralysis
agitans syndrome of non-drug immunogenicity, and in better light, severe, or
the elderly poor.
3. Treat parkinsonism and Pakinsonism syndrome,
hepatic coma,hub functions to improve the patient awake, symptom improvement.
4. Mucuna Pruriens Extract is anti-paralysis agitans.
Through the blood-brain barrier into the brain tissue, but by the
decarboxylation of l-dopa decarboxylase into dopamine, play a role.
5. Mucuna Pruriens Extract is used for essential tremor and paralysis paralysis agitans syndrome of non-drug immunogenicity, and in better light, severe, or the elderly poor.
Levodepa specification
ANALYSIS |
SPECIFICATIONS |
RESULTS |
Assay |
Levodopa L-Dopa≥99% |
99.15% HPLC |
Organoleptic & Physical Characteristics |
||
Extract Solvent |
Water& Alcohol |
Complies |
Particle size |
100% pass 80 mesh |
Complies |
Loss on Drying |
<5.0% |
0.33% |
Appearance |
White Fine Powder |
Complies |
Pesticides |
Negative |
Complies |
Residual Solvent |
<0.5% |
Complies |
Ash |
<5.0% |
0.45% |
Odor |
Characteristic |
Complies |
Levodepa Heavy metals |
||
Total Heavy Metals |
≤10.00PPM |
Complies |
Arsenic |
≤5.00 PPM |
Complies |
Levodepa Microbiological Tests |
||
Total Plate Count |
≤1000cfu/g |
Complies |
Salmonella |
Negative |
Negative |
Total Yeast & Mold |
≤100cfu/g |
Complies |
E.Coli |
Negative |
Negative |