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Product Name:Chondroitin sulfate
Chondroitin sulfate source: Chondroitin sulfate is a chemical that is normally found in cartilage around joints in the body. Chondroitin sulfate is manufactured from animal sources, such as cow cartilage.
Chondroitin sulfate introduction: Chondroitin sulfate is a major component of extracellular matrix, and is important in maintaining the structural integrity of the tissue. This function is typical of the large aggregating.
As part of aggrecan, Chondroitin sulfate is a major component of cartilage. The tightly packed and highly charged sulfate groups of Chondroitin sulfate generate electrostatic repulsion that provides much of the resistance of cartilage to compression. Loss of Chondroitin sulfate from the cartilage is a major cause of osteoarthritis.
Appearance: white to off-white powder
Chondroitin sulfate specifications: 90% 95% 98% chondroitin Sulfate chondroitin >95%, Calcium>6.5%; Sodium<0.5%
Test By: HPLC/CPC
Molecular formula: (C12H21NO14S) n
Molecular weight: 30000-50000
Structural formula:
1.As a health food or health care drugs, Chondroitin sulfate is used to cure coronary heart disease, angina, myocardial infarction, coronary atherosclerosis, myocardial ischemia and Other diseases in the long-term, no obvious side effects, can significantly reduce the incidence of coronary heart disease and mortality.
2. Chondroitin sulfate for the treatment of neuralgia, nerve migraine, joint pain, arthritis and scapular joint pain, and abdominal pain after the operation.
3. To prevent and treat hearing impairment which caused by streptomycin and a variety of noise-induced hearing difficulties, tinnitus effectively.
4. It can aid in healing chronic nephritis, chronic hepatitis, keratitis and corneal ulcer,etc.
5. Chondroitin in bovine cartilage can cure anti-tumor. In addition, Chondroitin sulfate is also used in cosmetics, and traumatic wound healing agent.
6. Chondroitin sulfate is also used in eye drops.
Chondroitin sulfate specification
|
ITEMS |
STANDARD |
RESULTS |
|
Appearance |
White to Off-white Free Flowing Powder |
PASS |
Clarity and Color of Solution |
0.35 Max at 420nm |
PASS |
|
Specific Rotation |
-20.0° — -30.0° |
-23.0° |
|
PH |
5.5-7.5 |
6.4 |
|
Loss On Drying |
10% Max |
8.5% |
|
Chondroitin Sulfate Assay (HPLC) |
90% Min ( O.D.B) |
90.2% |
|
Content of Protein |
6.0% Max (Dried Basis) |
3.3% |
Residue On Ignition |
20%-30% |
22.0% |
|
Chondroitin Sulfate Assay (CPC) |
90% Min ( O.D.B) |
91.6% |
|
Bluk density |
0.6Min |
0.63 |
|
Particle size |
100%through 80mesh |
PASS |
|
Heavy Metals (Pb) |
20PPM Max |
PASS |
|
Sulfate |
0.24% Max |
PASS |
|
Chloride |
0.5% Max |
PASS |
|
Chondroitin sulfate Microbiological Tests |
||
|
E.Coli |
Negative |
NEGATIVE |
|
Total Plate Count |
1,000cfu/g Max |
PASS |
|
Clostridium |
Negative |
NEGATIVE |
|
Salmonella |
Negative |
NEGATIVE |
|
Yeast & Mold |
100cfu/g Max |
PASS |
